The intersections at LaTrobe and Elizabeth streets, Flinders and Swanston streets and Collins and Spring streets have been identified as hotspots for bicycle accidents.
According to an interactive map released by Melbourne University, the CBD is a high risk area for cyclists.
Within the City of Melbourne, there have been almost 2000 crashes between vehicles and cyclists between 2010 and 2018, a much larger number than any other municipality in Victoria.
In the CBD, LaTrobe, Swanston, Flinders, Collins and Lonsdale streets have the most accidents involving bikes.
Researchers say the lack of adequate cycling infrastructure, including bike lanes, and speed limits, contribute to the high number of crashes in these locations.